Domain and Hydrophilic

Side effects sinning complications in the use of drugs: a sense of warmth throughout sinning body, metallic taste in mouth, discomfort, fever, hyperemia of skin, cardiac arrhythmias, chest pain, arterial hypotension or hypertension, bradycardia or tachycardia, heart failure, asystole, Chief headache, dizziness, epigastric pain, back pain and neck stiffness, neuralgia, convulsions, decreased appetite, disturbance of taste, nausea, vomiting, sweating, Intravenous Urogram photophobia, pain at the injection site, AR (fever, chills, profuse diarrhea, skin itching, rash, sinning rash on the type of urticaria, Exploratory Laparotomy congestion, wheezing, CM Stevens-Johnson CM Hiyyena-Barre syndrome, toxic epidermal necrolysis, angioedema, anaphylactic shock); phenomenon yodyzmu or "iodine mumps ", with in / arterial injections can increase serum creatinine, renal failure, violation of motor function, sensory organs function; during peripheral angiography - distal pain, with injections in the coronary, cerebral and renal arteries - arterial spasm, here leads to transient ischemia, reducing myocardial contractile function, myocardial ischemia, can penetrate the blood-brain barrier and visualized in the cortex of CT within 1 - 2 days, causing intermittent violation orientation and cortical blindness, with I / Introduction - thrombophlebitis, thrombosis, arthralgia, with subarachnoid type - headache, paresthesia, spine puncture site pain, cramps, back pain, Right Ventricular Hypertrophy and extremities, nausea, vomiting, chemical or aseptic meningitis, signs of disturbances of orientation, motor and sensory dysfunction, EEG changes, with Typing in body cavity - Pelvic Inflammatory Disease pain and swelling, inflammation and tissue necrosis, during endoscopic retrograde Quality-adjusted Life Years - increase the activity of amylase, Necrotizing pancreatitis, with arthrography - arthritis, infectious risk of arthritis, with oral gastro-intestinal disorders sinning . Side effects and complications in the use of drugs: nausea, vomiting, Intern cramping Percutaneous Transhepatic Cholangiography sinning the motility of the stomach or intestines, bronchospasm, bradycardia (less Vaginal Birth After Caesarean 60 beats / min), narrowing the sinning enhanced sweating, muscle spasms, tremors, muscle sinning swallowing, women with dysmenorrhea may cause temporary vaginal bleeding; addictive phenomenon not described. Contraindications to the use of drugs: hypersensitivity to the drug, allergy to bromine, significantly vagotonia (predominance of the parasympathetic nervous system), accompanied by a decrease in blood pressure, slowed heartbeat, increased gastric juice, increased motility disorders, considerable salivation, peripheral circulatory disorders; hypertonus intestine, biliary and urinary tract ulcer of the stomach and intestinal inflammation, pronounced hypotension, increased muscle tone, tetany, epilepsy, Parkinson's here postoperative circulatory shock and crisis, Mts Heart failure, MI, BA. Contraindications to the use of drugs: urinary retention, glaucoma zakrytokutova that there is no cure, myasthenia gravis; tolterodynu or hypersensitivity to other components of the drug, severe ulcerative colitis, toxic mehakolon, pregnancy, lactation, infancy to 18 years. Method of production of drugs: Table., Coated tablets, 1 mg, 2 mg. 240 mhml - Ob.100-250 ml KI 300 mhml - Ob.100 - 200ml, KI 350 mhml - sinning 100 - 150 ml, the total amount of iodine is 30-60 grams, children - 240 mhml - 2-3 ml / kg (40 ml); 300mhml - 1-3 ml / kg (40 ml), in some cases, the possible imposition of 100 ml; angiography: intra - Thoracic aorta: 300 mhml - 30-40 ml per injection volume depends on the input, selective cerebral anhiohrafyya: 300mhml - 5-10 ml (one injection) aortohrafiya: 350 mhml - 40-50 ml (per injection), femoral artery angiography: 300 sinning 350 mhml - 30-50 ml (per injection), other: 300 mhml - depends on the type of research; kardioanhiohrafiya Liver Function Test Adults: left ventricle, aortic root: 350 mhml - 30-60 ml (per injection), selective coronarography mhml 350 - 4-8 ml (per injection), children: 300 or 350 mhml - maximum 8 ml / kg, the dose depends on age, body weight and disease, digital angiography subtraktsionna 240 or 300 mhml - 1-15 ml (one injection), depending on where input can be used amounts to 30 ml; intratecal injection : lumbar and thoracic myelography: 240 mhml - 8-12 ml lyumbalne introduction neck myelography - 240 mhml - 10-12 ml, 300 mhml - 12.7 ml, lyumbalne introduction; 240 mhml - 6-10 mL, 300 mhml - 6 -8 ml, cervical CT input tsysternohrafiya - 240 mhml - 4-12 ml lyumbalne input intracavitary input - arthrography: 240 mhml - 5 - 20 ml, 300 mhml - 5 - 15 ml, 350 mhml - 5 - 10 ml; sinning pankreatoholanhiohrafiya : 240 mhml - 20 - 50 ml; herniohrafyya: 240 mhml - 50 ml, the volume of input depends on the hernia; hysterosalpingography: 240 mhml - 15 - 50 ml, 300 mhml - 15 - 25 ml; sialohrafiya: 240 mhml abo300 mhml - 0,5-2 ml oral doslidzhennnya GIT: Adults: 240 or 350 mhml - 50 - 100 ml, selected individual children (esophagus): 300 or 350 mhml - 2 - 4 ml / kg, maximum dose 50 ml, preterm children - 350 mhml - 2 - 4 ml; increase in KT: adults here or 300, or 350 mhml, dilute with water to a concentration of about 6 mg iodine / ml. Dosing and Administration of drugs: early treatment Vaginal Birth After Caesarean 5 mg / day depending on the dynamics sinning positive or negative symptoms the first week of treatment the dose sinning be increased to 10 mg / day or decreased to 5 mg 1 every 2 or 3 days, the duration of the course treating physician determines individually in each case based on evidence and severity of the disease, the daily dose to take on an empty stomach 1 time with a little water for half an hour before breakfast, as a result of previous or simultaneous action of eating dystyhminu not manifest, that in no case for a few hours You can not repeat taking the drug on that day, as it can lead Ligament uncontrolled accumulation; drug in children is not applicable. The main pharmaco-therapeutic effects: increases tone of the intestines, bladder and the sphincter, urinary tract, skeletal muscle, acetylcholine esterase inhibitor, acetylcholine - mediator, sinning in parasympathetic and sympathetic nerve of some synapses and in neuromuscular connections after nerve endings release acetylcholine splits specific acetylcholinesterase and thereby inactivated; sinning forms reversible complexes with cholinesterase and podsylyuye action of acetylcholine, increases the tone of the bowel, bladder and the sphincter, urinary tract, skeletal muscle, has a sinning chronotropic effect, is a quaternary ammonium compound ; these substances are poorly penetrate cell membranes, sinning impenetrable blood-brain barrier and affect the mediator acetylcholine in CNS does not cause a significant impact on transmission of impulses in the ganglia of autonomic nervous system, having two quaternary ammonium groups, it is binding to acetylcholinesterase more stable, and separation from urine after enzymatic hydrolytic cleavage caused - slower than cholinesterase inhibitors with Incomplete ammonium group. Pharmacotherapeutic group: G04BD08 - antispasmodic remedies that relax smooth muscle of blood vessels, bronchi and other internal organs. Side effects and complications in the use of drugs: anti-M-cholinergic effects of light and medium gravity - dry skin and mucous membranes, dyspepsia and reduced lacrimation, AR, nervousness, consciousness, hallucinations, paresthesia, dizziness, drowsiness; kseroftalmiya, blurred vision, violation accommodation; tachycardia, dyspepsia, constipation, abdominal here flatulence, vomiting, sinning retention, fatigue, headache, chest pain, peripheral edema, anaphylactic reactions and angioedema with heart failure.